International research breakthrough: 235 metabolites can predict the risk of diabetes
2021-11-12
In February, the top international journal Nature Medicine published a large-scale metabonomics study on diabetes, led by Harvard University and other international teams, integrating data from 23634 people in 10 countries, and tracking for 26 years. The study found that among 469 metabolites, 235 were significantly associated with the risk of diabetes, of which 67 were first discovered, involving multiple metabolic pathways such as bile acid and lipid. The study also developed risk characteristics composed of 44 metabolites, which can more accurately predict future diabetes risk than traditional risk factors, capture metabolic abnormalities that cannot be reflected by traditional indicators, and provide a new tool for personalized prevention of diabetes. The study also emphasizes that lifestyle has a significant impact on related metabolites, and reasonable exercise and healthy diet can effectively optimize the metabolite profile.
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